Abstract
Background
Diabetes is increasingly prevalent among women of reproductive age, yet little is
known about quality of diabetes care for this population at increased risk of diabetes
complications and poor maternal and infant health outcomes. Previous studies have
identified racial/ethnic disparities in diabetes care, but patterns among women of
reproductive age have not been examined.
Methods
This retrospective cohort study analyzed 2016 data from Kaiser Permanente Northern
California, a large integrated delivery system. Outcomes were quality of diabetes
care measures—glycemic testing, glycemic control, and medication adherence—among women
ages 18 to 44 with type 1 or type 2 diabetes (N = 9,923). Poisson regression was used to estimate the association between patient
race/ethnicity and each outcome, adjusting for other patient characteristics and health
care use.
Results
In this cohort, 83% of participants had type 2 diabetes; 31% and 36% of women with
type 2 and type 1 diabetes, respectively, had poor glycemic control (hemoglobin A1c
of ≥9%), and approximately one-third of women with type 2 diabetes exhibited nonadherence
to diabetes medications. Compared with non-Hispanic White women with type 2 diabetes,
non-Hispanic Black women (adjusted risk ratio, 1.2; 95% confidence interval, 1.1–1.3)
and Hispanic women (adjusted risk ratio, 1.2; 95% confidence interval, 1.1–1.3) were
more likely to have poor control. Findings among women with type 1 diabetes were similar.
Conclusions
Our findings indicate opportunities to decrease disparities and improve quality of
diabetes care for reproductive-aged women. Elucidating the contributing factors to
poor glycemic control and medication adherence in this population, particularly among
Black, Hispanic, and Asian women, should be a high research and practice priority.
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References
- Disparities in care delivery and outcomes in young adults with diabetes.Current Diabetes Reports. 2018; 18: 65
- Achievement of goals in U.S. diabetes care, 1999–2010.New England Journal of Medicine. 2013; 368: 1613-1624
- ACOG Committee Opinion No. 649: Racial and ethnic disparities in obstetrics and gynecology.Obstetrics and Gynecology. 2015; 126: e130-e134
- ACOG Practice Bulletin No. 201: Pregestational diabetes mellitus.Obstetrics and Gynecology. 2018; 132: e228-e248
- Complications.(Available:)www.diabetes.org/diabetes/complicationsDate accessed: November 22, 2019
- 6. Glycemic targets: Standards of medical care in diabetes—2018.Diabetes Care. 2018; 41: S55-S64
- 13. Management of diabetes in pregnancy: Standards of medical care in Diabetes—2018.Diabetes Care. 2018; 41: S137-S143
- 1. Strategies for improving care.Diabetes Care. 2016; 39: S6-S12
- 1. Promoting health and reducing disparities in populations.Diabetes Care. 2017; 40: S6-S10
- Hypertension and Diabetes in Non-Pregnant Women of Reproductive Age in the United States.Preventing Chronic Disease. 2019; 16: E146
- Trends in pre-pregnancy diabetes among deliveries in 19 U.S. states, 2000-2010.American Journal of Preventive Medicine. 2015; 48: 154-161
- Racial/ethnic disparities in diabetes diagnosis and glycemic control among women of reproductive age.Journal of Women’s Health (2002). 2018; 27: 1271-1277
- Racial/ethnic disparities in diabetes quality of care: The role of healthcare access and socioeconomic status.Journal of Racial and Ethnic Health Disparities. 2018; 5: 7-14
- National diabetes statistics report, 2017.Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, 2017 (Available:)www.cdc.gov/diabetes/data/statistics/statistics-report.htmlDate accessed: December 3, 2018
- Women’s reproductive health. At a glance reports.(Available:)www.cdc.gov/chronicdisease/resources/publications/aag/womens-reproductive-health.htmDate: 2017Date accessed: December 3, 2018
- Prevent complications. Living with diabetes.(Available:)
- 2019 Medicare-Medicaid plan performance data technical notes (p. 65).(Available:)
- Mail-order pharmacy use and adherence to diabetes-related medications.American Journal of Managed Care. 2010; 16: 33-40
- Similarity of the Adult Kaiser Permanente Membership in Northern California to the insured and general population in Northern California: Statistics from the 2011 California Health Interview Survey. Kaiser Permanente Northern California Division of Research.(Available:)https://divisionofresearch.kaiserpermanente.org/projects/memberhealthsurvey/SiteCollectionDocuments/chis_non_kp_2011.pdfDate: 2015Date accessed: January 30, 2019
- Racial and ethnic disparities in maternal morbidity and obstetric care.Obstetrics and Gynecology. 2015; 125: 1460-1467
- Unintended pregnancy in the United States.Guttmacher Institute, 2019 (Available:)www.guttmacher.org/fact-sheet/unintended-pregnancy-united-statesDate accessed: January 10, 2019
- Racial and economic disparities in diabetes in a large primary care patient population.Ethnicity & Disease. 2016; 26: 85-90
- Reducing disparities in severe maternal morbidity and mortality.Clinical Obstetrics and Gynecology. 2018; 61: 387-399
- Quality of care and disparities in obstetrics.Obstetrics and Gynecology Clinics of North America. 2017; 44: 13-25
- Impact of a pharmacy benefit change on new use of mail order pharmacy among diabetes patients: The Diabetes Study of Northern California (DISTANCE).Health Services Research. 2015; 50: 537-559
- Overestimation of risk ratios by odds ratios in trials and cohort studies: Alternatives to logistic regression.CMAJ: Canadian Medical Association Journal. 2012; 184: 895-899
- Adherence to diabetes medication: A systematic review.Diabetic Medicine. 2015; 32: 725-737
- Medication adherence does not explain Black-White differences in cardiometabolic risk factor control among insured patients with diabetes.Journal of General Internal Medicine. 2016; 31: 188-195
- Type 2 diabetes in adolescents and young adults.Lancet. Diabetes & Endocrinology. 2018; 6: 69-80
- Racial and ethnic disparities in maternal morbidity and mortality.Obstetrics and Gynecology. 2015; 125: 690-694
- Different approaches to the assessment of adherence and persistence with cardiovascular-disease preventive medications.Current Medical Research and Opinion. 2017; 33: 1329-1336
- Comorbid diabetes and severe mental illness: Outcomes in an integrated health care delivery system.Journal of General Internal Medicine. 2019; 35: 1-7
- Delivering family planning and preconception care to women with diabetes: Implementation challenges and promising strategies.Healthcare, Amsterdam, Netherlands)2019: 100386
- Contrasting measures of adherence with simple drug use, medication switching, and therapeutic duplication.Annals of Pharmacotherapy. 2009; 43: 36-44
- Health care experiences of pregnant, birthing and postnatal women of color at risk for preterm birth.Social Science & Medicine (1982). 2018; 201: 127-135
- Comprehensive diabetes care - NCQA.(Available:)www.ncqa.org/hedis/measures/comprehensive-diabetes-care/Date accessed: December 3, 2018
- HEDIS and performance measurement. NCQA.(Available:)www.ncqa.org/hedis/Date accessed: February 14, 2020
- NCQA health insurance plan Ratings 2016-2017.(Available:)http://healthinsuranceratings.ncqa.org/2016/HprPlandetails.aspx?id=44Date accessed: January 25, 2019
- Population-level factors associated with maternal mortality in the United States, 1997-2012.BMC Public Health. 2018; 18: 1007
- Prevalence of and racial disparities in risk factor control in older adults with diabetes: The Atherosclerosis Risk in Communities Study.Diabetes Care. 2015; 38: 1290-1298
- Trends and racial and ethnic disparities in the prevalence of pregestational type 1 and type 2 diabetes in Northern California: 1996-2014.American Journal of Obstetrics and Gynecology. 2017; 216: 177.e1-177.e8
- Association of age and comorbidity on 2009 influenza A pandemic H1N1-related intensive care unit stay in Massachusetts.American Journal of Public Health. 2014; 104: e118-e125
- Relationships between medication adherence and cardiovascular disease risk factor control in elderly patients with diabetes.Pharmacotherapy. 2017; 37: 1204-1214
- Outpatient electronic health records and the clinical care and outcomes of patients with diabetes mellitus.Annals of Internal Medicine. 2012; 157: 482-489
- Disparities in preconception health indicators - Behavioral Risk Factor Surveillance System, 2013-2015, and Pregnancy Risk Assessment Monitoring System, 2013-2014.Morbidity and Mortality Weekly Report. Surveillance Summaries. 2018; 67: 1-16
- Racial and ethnic disparities in prevalence and care of patients with type 2 diabetes.Clinical. 2017; 35: 66-70
- The HMO research network virtual data warehouse: A public data model to support collaboration.EGEMS. 2014; 2
- Population health management for diabetes: Health care system-level approaches for improving quality and addressing disparities.Current Diabetes Reports. 2017; 17: 31
- Medicare STAR excludes diabetes patients with poor CVD risk factor control.American Journal of Managed Care. 2014; 20: e573-e581
- Diabetes care and outcomes for American Indians and Alaska natives in commercial integrated delivery systems: A SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) Study.BMJ Open Diabetes Research & Care. 2014; 2: e000043
- The effectiveness of diabetes care management in managed care.American Journal of Managed Care. 2009; 15: 295-301
- Validation of an algorithm for identifying type 1 diabetes in adults based on electronic health record data.Pharmacoepidemiology and Drug Safety. 2018; 27: 1053-1059
- The ethics of perinatal care for Black women: Dismantling the structural racism in “mother blame” narratives.Journal of Perinatal & Neonatal Nursing. 2019; 33: 108-115
- Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010.Annals of Internal Medicine. 2014; 160: 517-525
- A systematic review of insulin adherence measures in patients with diabetes.Journal of Managed Care & Specialty Pharmacy. 2016; 22: 1224-1246
- Racial/ethnic disparities in diabetes care and outcomes: A mixed methods study.Journal of Health Disparities Research and Practice. 2018; 11
- Racial-Ethnic Disparities in Management and Outcomes Among Children With Type 1 Diabetes..Pediatrics. 2015; 135: 424-434
- Early onset type 2 diabetes: Risk factors, clinical impact and management.Therapeutic Advances in Chronic Disease. 2014; 5: 234-244
- Prevalence of diagnosed type 1 and type 2 diabetes among US adults in 2016 and 2017: Population based study.BMJ (Clinical Research Ed.). 2018; 362: k1497
- A modified Poisson regression approach to prospective studies with binary data.American Journal of Epidemiology. 2004; 159: 702-706
Biography
Cassondra J. Marshall, DrPH, MPH, is an Assistant Professor of Maternal, Child, and Adolescent Health at UC Berkeley School of Public Health. Her research interests include patient-centered family planning services and the prevention and management of chronic disease among women of reproductive age.
Biography
Hector P. Rodriguez, PhD, MPH, is Professor of Health Policy and Management, UC Berkeley School of Public Health. He specializes in organizational analysis and performance measurement in health care delivery and local public health systems.
Biography
Wendy Dyer, MS, is a senior data consultant at Kaiser Permanente Northern California Division of Research.
Biography
Julie A. Schmittdiel, PhD, MA, is a research scientist at Kaiser Permanente, Division of Research, specializing in diabetes care and prevention research. She is Director, Health Delivery Systems Center for Diabetes Translational Research, and Associate Director, Delivery Science Fellowship Program.
Article info
Publication history
Published online: April 24, 2020
Accepted:
March 13,
2020
Received in revised form:
March 12,
2020
Received:
May 28,
2019
Footnotes
Funded by The Permanente Medical Group and the Kaiser Permanente Northern California Division of Research. Dr. Schmittdiel received support from the Health Systems Center for Diabetes Translational Research (P30DK092924). The authors have no conflict of interests to report.
Identification
Copyright
© 2020 Jacobs Institute of Women's Health. Published by Elsevier Inc.