Abstract
Introduction
In 2016, 2.1 million people in the United States were estimated to have an opioid
use disorder. Although the disorder can be safely and effectively treated with prescription
methadone, treatment is potentially long term and may span women's peak childbearing
ages. Little is known about women's reproductive health needs while on methadone.
Methods
We interviewed 22 sexually active, nonpregnant women ages 21–39 years at two Los Angeles
methadone clinics in 2016. The interviews were transcribed and coded by four researchers
using thematic and open coding techniques.
Results
One-half of the women were nulliparous and 17 were in stable, monogamous relationships
with men. Women reported a range of feelings and perceptions about pregnancy, but
nearly all wanted to delay pregnancy until discontinuing methadone. However, many
women indicated limited interest in preventing pregnancy because of the relative stability
of their relationships, fear of infertility, and low perceived risk of pregnancy.
These factors influenced contraceptive use.
Discussion
Women described mixed feelings about pregnancy and many ultimately felt that an unplanned
pregnancy would be acceptable in the context of their relationships and uncertain
fertility. These findings provide context for previous quantitative findings that
women in methadone treatment have higher rates of unintended pregnancy and lower rates
of contraceptive use than the general population.
Conclusions
Accurate information about pregnancy in the context of methadone treatment may help
women to make proactive family planning decisions. Health care providers should discuss
the guidelines for pregnancy on methadone and offer a range of options to help women
achieve their reproductive goals.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Women's Health IssuesAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Trends in the Use of methadone and buprenorphine at substance abuse treatment facilities: 2003 to 2011.in: The CBHSQ Report. Substance Abuse and Mental Health Services Administration (US), Rockville, MD2013 (Available:) (Accessed: August 1, 2018)
- Opioid use and opioid use disorder in pregnancy. Committee Opinion No. 711.Obstetrics and Gynecology. 2017; 130: e81-e94
- Diagnostic and statistical manual of mental disorders.5th ed. American Psychiatric Publishing, Arlington, VA2013
- U.S. Medical eligibility criteria for contraceptive use, 2016.MMWR Recommendations and Reports. 2016; 65: 1-104
- Narcotic-induced hypogonadism during therapy for heroin addiction.Journal of Addictive Diseases. 2002; 21: 47-53
- Effect of methadone maintenance treatment on heroin craving, a literature review.Journal of Addictive Diseases. 2010; 30: 27-38
- Declines in unintended pregnancy in the United States, 2008-2011.New England Journal of Medicine. 2016; 374: 843-852
- Medication-assisted treatment with methadone: Assessing the evidence.Psychiatric Services. 2014; 65: 146-157
- Unintended pregnancy in opioid-abusing women.Journal of Substance Abuse Treatment. 2011; 40: 199-202
- A 33-year follow-up of narcotics addicts.Archives of General Psychiatry. 2001; 58: 503-508
- Neonatal drug withdrawal.Pediatrics. 2012; 129: e540-e560
- A 25-year follow-up of patients admitted to methadone treatment for the first time: Mortality and gender differences.Addictive Behaviors. 2011; 36: 1184-1190
- Methadone maintenance vs. methadone taper during pregnancy: Maternal and neonatal outcomes.American Journal on Addictions. 2008; 17: 372-386
- Methadone maintenance treatment (MMT): A review of historical and clinical issues.Mount Sinai Journal of Medicine, New York. 2000; 67: 347-364
- Biological basis of sex differences in drug abuse: Preclinical and clinical studies.Psychopharmacology. 2002; 164: 121-137
- Gender differences in trends for heroin use and nonmedical prescription opioid use, 2007–2014.Journal of Substance Abuse Treatment. 2018; 87: 79-85
- Women and opioids: Something different is happening here.Lancet. 2018; 392: 9-11
- Principles of drug addiction treatment: A research-based guide, 3rd ed.(Available:) (Accessed: August 1, 2018)
- Arrests of and forced interventions on pregnant women in the United States, 1973-2005: Implications for women’s legal status and public health.Journal of Health Politics, Policy and Law. 2013; 38: 299-343
- Family planning in substance use disorder treatment centers: Opportunities and challenges.Substance Use & Misuse. 2016; 51: 1477-1483
- Chronic opioid use during pregnancy: Maternal and fetal implications.Clinics in Perinatology. 2013; 40: 337-350
- Pregnant women and substance use: Fear, stigma, and barriers to care.Health & Justice. 2015; 3: 2
- Key substance use and mental health indicators in the United States: Results from the 2016 National Survey on Drug Use and Health. HHS Publication No. SMA 17-5044, NSDUH Series H-52.(Available:)https://www.samhsa.gov/data/(Accessed: August 1, 2018)Date: 2017
- Patient-centered care to address barriers for pregnant women with opioid dependence.Obstetrics and Gynecology Clinics of North America. 2017; 44: 95-107
- Emergency Visits for prescription opioid poisonings.Journal of Emergency Medicine. 2015; 49: 871-877
- Contraceptive use and method choice among women with opioid and other substance use disorders: A systematic review.Preventive Medicine. 2015; 80: 23-31
- Reproductive health needs among substance use disorder treatment clients.Journal of Addiction Medicine. 2016; 10: 20
- Stigma among health professionals towards patients with substance use disorders and its consequences for healthcare delivery: Systematic review.Drug & Alcohol Dependence. 2013; 131: 23-35
- The effects of opioids and opioid analogs on animal and human endocrine systems.Endocrine Reviews. 2010; 31: 98-132
- Treating pregnant women dependent on opioids is not the same as treating pregnancy and opioid dependence: A knowledge synthesis for better treatment for women and neonates.Addiction. 2008; 103: 1429-1440
Biography
Marta Bornstein, MPH, is a PhD student in the Department of Community Health Sciences at the UCLA Fielding School of Public Health. Her research focuses on sexual and reproductive health, both in the United States and internationally.
Biography
Jessica D. Gipson, MPH, PhD, is an Associate Professor in the Department of Community Health Sciences at the UCLA Fielding School of Public Health. Her research focuses on sexual and reproductive health of marginalized communities and populations.
Biography
Roselle Bleck, BA, is a medical student, UCLA David Geffen School of Medicine, and is pursuing an MPH in Health Policy, Columbia University's Mailman School of Public Health. She will devote her career to women's health, focusing on access to reproductive health care.
Biography
Aparna Sridhar, MD, MPH, is an Assistant Professor in the Department of Obstetrics and Gynecology at the UCLA David Geffen School of Medicine. Her research interests are focused on contraception, family planning, and the development of patient education tools.
Biography
Agatha Berger, MD, MPH, is a faculty member of the Department of Obstetrics & Gynecology, Christiana Care Health System, Newark, Delaware. Her research interests include the impacts of substance use disorders on women's reproductive health and lives and to reproductive health care.
Article info
Publication history
Published online: November 13, 2018
Accepted:
October 10,
2018
Received in revised form:
September 18,
2018
Received:
March 24,
2018
Footnotes
The views and opinions expressed are those of the authors and do not necessarily represent the views and opinions of funders.
This was funded via a grant from the Society of Family Planning Research Fund and Grants and support from NICHD Center grant P2C-HD041022 and Training grant T32-HD007545.
Identification
Copyright
© 2018 Jacobs Institute of Women's Health. Published by Elsevier Inc.